- 英文名称
- Simendan
- 分子式
- C14H12N6O
- 分子量
- 280.29
- 中文别名
- 左西孟旦; (R)-(-)-[[4-(1,4,5,6-四氢-4-甲基-6-氧代-3-哒嗪基)苯基]-肼叉]丙二腈; 6-(4-氨基苯基)-5-甲基-4,5-二氢-3(2H)-哒嗪酮; Mesoxalonitrile (±)-(p-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazone; (±)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile; LEVOFLUOROCARBOXYLICACID; {2-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]hydrazinylidene}propanedinitrile; {[4-(4-Methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridazinyl)phenyl]hydrazono}malononitrile; levosimendan; Propanedinitrile, 2-[2-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazinylidene]-; Propanedinitrile, ((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)-; simendanum; 1-cyano-N-(4-(6-hydroxy-4-methyl-4,5-dihydropyridazin-3-yl)phenyl)methanecarbohydrazonoyl cyanide; Simendan [INN]; 2-[[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile; Levosimendan Impurity 16; Simsndan; OR-1259; (4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide; [4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]carbonohydrazonoyl dicyanide
- 用途
- 生命科学；作为钙增敏剂用于治疗各种急性心力衰竭病症，如心脏手术后或扩张性心肌病的心衰；可增强心肌收缩力，不增加心肌耗氧量，改善血流动力学、心律不齐等症状，缩短住院时间，与其他心血管药物相互作用少，安全性好。
