- 英文名称
- N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)-2-phenoxyacetamide
- 分子式
- C30H45N5O8Si2
- 分子量
- 659.88
- 中文别名
- N-(苯氧基乙酰基)-3',5'-O-[1,1,3,3-四(异丙基)-1,3-二硅氧烷二基]鸟苷; 3',5'-TIPS-N-PAC-鸟苷; 3',5'-TIPS-PAC-鸟苷; Guanosine,N-(phenoxyacetyl)-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]; 3,5-TIPS-N-PAc-Guanosine; 3',5'-TIPS-N-PAc-Guanosine; N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide; N2-Phenoxyacetyl-3',5'-TIPS-guanosine; N2-Phenoxyacetyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-guanosine; N2-Phenoxyacetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine; 5',3'-tetraisopropyl disiloxane-riboguanosine(N-PAC); 3',5'-TIPS-PAc-rG; N-(Phenoxyacetyl)-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine; 3',5'-TIPS-N-PAC-G; N2-Pac-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-guanosine; N2-Pac-3',5'-TIPDS-Gr
- 用途
- 作为鸟嘌呤核苷类似物，具有免疫刺激活性，在动物模型中诱导I型干扰素产生抗病毒作用，其功能活性依赖于活化Toll样受体7(TLR7)。
