- 英文名称
- CRANAD-2
- 分子式
- C23H25BF2N2O2
- 分子量
- 410.26
- 中文别名
- 化合物CRANAD 2; (T-4)-[(1E,6E)-1,7-双[4-(二甲基氨基)苯基]-1,6-庚二烯-3,5-DIONATO-ΚO3,ΚO5]二氟硼; (T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-κO3,κO5]difluoroboron; CRANAD 2; Cranad-2; [4-[(2Z)-2-[6-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2,2-difluoro-1,3-dioxa-2-boranuidacyclohex-5-en-4-ylidene]ethylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium; 4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(N,N-dimethylaniline); (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron; 4,6-bis(4-dimethylaminophenyl styryl)-2,2-difluoro-(1,3,2)dioxaborinin-4-ene-1-ium-2-uide; Boron, [(1E,6E)-1,7-bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-κO3,κO5]difluoro-, (T-4)- (ACI)
- 用途
- CRANAD-2 是检测 Aβ 斑块的特异性近红外荧光探针，可穿透血脑屏障，对 Aβ 聚集体具有高度亲和力，其 Kd 值为 38 nM，用于 Aβ 斑块的检测。
