医药索非布韦中间体；化学合成及生命科学领域原料；作为氨基酸衍生物易被植物吸收，不留残毒，不污染水源，伴有促进植物生长的作用，对农作物有增产效果；应用于食品、化妆品时，代谢产物无常见抗菌剂副作用，可提供营养成分，保护人体健康。
医药; 生命科学; 农业; 食品; 化妆品
路线1：直接酯化法
- 步骤：向装有机械搅拌器、回流冷凝器、温度计和氮气氛的烧瓶中加入（L）-丙氨酸（5.0g，56.1mmol）和氯化氢异丙醇溶液（11.1％w/w，73.8g，224.5mmol），加热至80-85℃反应4小时；TLC（7：3乙醇-水，茚三酮显色）确认转化完成后，真空浓缩除去异丙醇，残余物用乙酸异丙酯多次共蒸发，得产物9.4g。
- 条件：80-85℃；4h；惰性气氛。
- 收率：100%。
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