化学合成。
化学合成
合成路线 1（1. 合成：13031-60-2）
产率：96%
合成条件：at 0 - 20℃; for 2 h; Cooling with ice
实验步骤：通用方法：在冰浴下，向氨基取代的脂肪酸衍生物10a-10d（10mmol）的20mL甲醇溶液中滴加亚硫酰氯（20mmol）。 在室温下搅拌约2小时后，蒸发溶液，得到所需产物11a-11d。 4-氨基丁酸甲酯盐酸盐（11a）。 白色固体; 产率96.0％; 1 H NMR（400MHz，D 2 O）d 3.46（s，3H），2.79（t，J = 7.6Hz，2H），2.28（t，J = 7.3Hz，2H），1.77-1.67（m，2H）。 ESI-MS：[M + H-HCl] + m / z计算值：118.1，实测值：118.1。
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