5-溴-2-氟苯胺用作有机、医药中间体；也可用作分析试剂、中和剂、生物碱浸出剂，用于某些元素（如铜、镍）的检定和测定，可沉淀各种元素的氢氧化物，还用于制备铵化合物和洗涤剂。
有机中间体; 医药中间体; 分析试剂; 中和剂; 生物碱浸出剂; 元素检定与测定; 氢氧化物沉淀剂; 铵化合物制备; 洗涤剂
合成路线1
- 原料：5-溴-2-氟硝基苯（698g）、铁粉（711g）、饱和氯化铵水溶液（2.0L）、95%乙醇（0.90L）
- 步骤：将5-溴-2-氟硝基苯溶于95%乙醇中，加入铁粉与饱和氯化铵水溶液的混合体系；70℃搅拌24小时（HPLC监测反应完全）；冷却至室温，硅藻土过滤，滤液减压浓缩；残余物用乙酸乙酯（2L）和水（2L）液-液萃取，水相再用乙酸乙酯（1L）萃取；合并有机相，水（1L）洗涤，无水硫酸镁干燥，过滤后减压浓缩；高真空处理5小时除残留乙酸乙酯，得545.76g产物。
- 条件：70℃，24小时，乙醇-水混合溶剂体系，铁粉-氯化铵还原体系
- 收率：91%
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