65854-91-3 N-新戊酰基对氯苯胺

危险性质：非危险化学品

N-新戊酰基对氯苯胺作为中间体或活性成分，在医药和农药领域有重要应用，具体用途需参考相关专利及文献。

医药; 农药

合成路线 1（1. 合成：65854-91-3）

产率：99.7% 合成条件：With sodium hydrogencarbonate In water; ethyl acetate at 15 - 20℃; for 2 h; 实验步骤：参考实施例2将N-新戊酰基 - 对氯苯胺CAB（113kg，886mol），城市用水（565L）和碳酸氢钠（89.3kg，1.2当量）加入到乙酸乙酯（1695L）和新戊酰氯（112kg）中 在15℃或更低温度下向其中滴加1.05当量），并将溶液在约25℃下搅拌2小时。 分离各层后，用市政水（848L×2）洗涤有机层，并在减压下浓缩至约600L。 向其中加入乙基环己烷（848L），并在减压下再次浓缩至约600L。 将残余物冷却至约5℃，搅拌至成熟1小时。 过滤收集沉淀的晶体，减压干燥，得到标题化合物（187kg，收率99.7％）。 参考文献：

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