623-33-6 甘氨酸乙酯盐酸盐

运输信息：常温运输。危险描述：非危险化学品（sinopharm_reagent）；WGK Germany:3，RTECS号:MC0525000，TSCA listed，海关编码:29224995，存储类别:11 - 可燃固体，危险性类别:严重眼损伤 类别1（chemicalbook）；危险标志:GHS05，危险性描述:H318，危险性防范说明:P280; P305 + P351 + P338，信号词:Danger（molbase）。

甘氨酸乙酯盐酸盐用作农药菊酯类杀虫剂及制药工业原料，例如制备菊酸和二氯菊酸、杀菌剂异菌脲、医药消炎药、四唑乙酸等的中间体，也用于生化研究等制剂。

医药; 农药

路线1：亚硫酰氯法

• 步骤：在-10℃下将247.3g亚硫酰氯和130g甘氨酸加入到1000ml乙醇中。除去冰浴后，分批加入另外等量的甘氨酸。然后将混合物在回流下搅拌2小时。冷却至室温后，在旋转蒸发器上除去过量的醇和亚硫酰氯。向所得白色固体中再加入乙醇两次，然后在旋转蒸发器上除去乙醇，以完全除去粘附的亚硫酰氯。用乙醇重结晶后，得到218.6g（理论值的90.4％）标题化合物。
• 条件：-10 - 20℃；2小时；加热/回流
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