激素及前列腺素等-化工词典

激素及前列腺素等

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(1aS,4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,7-二羟基-4a,6a-二甲基-1a,4,4a,4b,5,6,6a,7,8,9,9a,9b,10,11-十四氢环戊烷并[7,8]菲并[1,10a-b]环氧基-3-碳腈
英文名称
(1aS,4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,7-Dihydroxy-4a,6a-dimethyl-1a,4,4a,4b,5,6,6a,7,8,9,9a,9b,10,11-tetradecahydrocyclopenta[7,8]phenanthro[1,10a-b]oxirene-3-carbonitrile
CAS号
13647-35-3
分子式
C₂₀H₂₇NO₃
分子量
329.43
中文别名
曲洛司坦;曲龙斯坦; MODRASTANE; (4a,5a,17b)-4,5-Epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile; 2a-Cyano-4a,5a-epoxyandrostan-17b-ol-3-one; Desopan; Trilostane; MFCD00199295; Modrenal; (4α,5α,17β)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile; Modrefen; Vetoryl; EINECS 237-133-0; 4α,5-Epoxy-3,17β-dihydroxy-5α-androst-2-ene-2-carbonitrile; Trilostane(Win 24540; Modrastane)
用途
曲洛斯坦可抑制皮质激素合成过程中的3β-脱氢酶，使皮质醇、醛固酮合成减少，临床用于治疗库欣综合征（皮质醇增多症）和原发性醛固酮增多症；对激素依赖性乳腺癌，通过调节雌激素受体亚型结合，发挥α-雌激素受体抑制剂和β-雌激素受体激动剂双重效应，用于治疗晚期乳腺癌，延缓疾病进展。
相关属性
基本信息物化属性
(2S,6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-2-氟-7-羟基-8b-(2-羟基乙酰基)-6a,8a,10,10-四甲基-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-十四氢-4H-萘[2',1':4,5]茚并[1,2-d][1,3]二氧杂戊环-4-酮
英文名称
(2S,6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-2-Fluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
CAS号
1524-88-5
分子式
C₂₄H₃₃FO₆
分子量
436.51
中文别名
Flurandrenolide; flurandrenolide; Fludroxycortide; Flurandrenolone; Cordran; Haelan; Fluorandrenolone; Drenison; Drocort; Sermaka; Flurandrenolone acetonide; Fluorandrenolone acetonide; Haldrone-F; Alondra-F; Fludroxicortida; Fludroxycortidum; CORDRAN SP; Fludroxicortide; DTXSID2047434; 8EUL29XUQT; L 33379; Acetonide of 6alpha-fluoro-16alpha-hydroxyhydrocortisone; 6alpha-Fluoro-16alpha-hydroxyhydrocortisone 16,17-acetonide; 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with acetone; NSC-757869; 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxyprogesterone cyclic 16,17-acetal with acetone; Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-; Pregn-4-ene-3,20-dione, 6alpha-fluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone; DTXCID0027434; Pregn-4-ene-3,20-dione, 6-alpha-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone; (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-17-en-16-one; Haelan-c; Haelan-x; (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo(10.8.0.0^(2,9).0^(4,8).0^(13,18))icos-17-en-16-one; RefChem:57098; D07AC07; 216-196-8; Fludroxicortidum; Fludrossicortide [DCIT]; Fludroxycortidum [INN-Latin]; Fludroxicortida [INN-Spanish]; Fludroxycortide [INN]; MLS000069556; MLS001148136; (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one; SMR000058825; Floudroxycortide; Fludrossicortide; Flurandrenolide [USAN]; (2S,6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-2-fluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one; HSDB 3084; Flurandrenolide (USP); CORDRAN (TN); Fludroxycortide; Flurandrenolone; EINECS 216-196-8; UNII-8EUL29XUQT; Fludroxycortide (JAN/INN); Fludroxycortid; Flurandrenolide [USAN:USP]; NCGC00016586-01; CAS-1524-88-5; Prestwick_1065; Opera_ID_1618; Prestwick0_000645; Prestwick1_000645; Prestwick2_000645; Prestwick3_000645; Flurandrenolide (Standard); SCHEMBL4694; FLURANDRENOLIDE [MI]; BSPBio_000649; FLUDROXYCORTIDE [JAN]; FLURANDRENOLIDE [HSDB]; SPBio_002570; FLURANDRENOLIDE [VANDF]; BPBio1_000715; CHEBI:5127; GTPL7606; orb1679011; FLUDROXYCORTIDE [MART.]
用途
用于缓解糖皮质激素反应性皮肤病（尤其是干燥、脱屑的局限性病变）的炎症和瘙痒症状；作为外用糖皮质激素，专用于治疗皮肤过敏性疾病，外用涂于患处，制剂形式包括霜剂（0.05%，含丙二醇）、贴剂（4 μg/sq cm）、洗剂（0.05%，含苯甲醇）、软膏（0.05%）等，原料药为白色或类白色粉末。
相关属性
基本信息物化属性
(3S,6S,9S,12S,15S,18S)-3-((1H-咪唑-5-基)甲基)-18-((1H-吲哚-3-基)甲基)-1-((1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-氨基-7-(4-氨基丁基)-39-苄基-4-(2-羧乙基)-10-(羧甲基)-42-(4-羟基苄基)-19,22,28-三(羟甲基)-16-异丁基-45-异丙基-13-(2-(甲硫基)乙基)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-十四氧代-33,34,49,50-四硫杂-2,5,8,11,14,17,20,23,26,29,37,40,43,46-十四氮杂双环[23.22.4]五十一烷-36-基)-12,15-二((S)-仲丁基)-9-(羧甲基)-6-异丁基-1,4,7,10,13,16-六氧代-2,5,8,11,14,17-六氮杂十九烷-19-酸
英文名称
(3S,6S,9S,12S,15S,18S)-3-((1H-Imidazol-5-yl)methyl)-18-((1H-indol-3-yl)methyl)-1-((1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-42-(4-hydroxybenzyl)-19,22,28-tris(hydroxymethyl)-16-isobutyl-45-isopropyl-13-(2-(methylthio)ethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontan-36-yl)-12,15-di((S)-sec-butyl)-9-(carboxymethyl)-6-isobutyl-1,4,7,10,13,16-hexaoxo-2,5,8,11,14,17-hexaazanonadecan-19-oic acid
CAS号
117399-94-7
分子式
C₁₀₉H₁₅₉N₂₅O₃₂S₅
分子量
2491.9
中文别名
生化试剂H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH; MFCD00133305; CSCSSLMDKECVYFCHLDIIW; Endothelin 1 (swine, human)
用途
内皮素1（ET-1）是具有人和猪内皮素1序列的合成肽，是有效的内源性血管收缩剂，通过ETA和ETB受体发挥作用，可引起血管平滑肌细胞纤维化、活性氧生成及促炎机制，用于研究内皮素1的生物活性及相关调节机制。
相关属性
基本信息物化属性
(3S,8R,9S,10R,13S,14S,17R)-17-乙炔基-13-甲基-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊并[a]菲-3,17-二基二乙酸酯
英文名称
(3S,8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate
CAS号
297-76-7
分子式
C₂₄H₃₂O₄
分子量
384.51
中文别名
双醋炔诺醇; Metrodiol diacetate; Ethinodiol diacetate; Ovulen; Continuin; Metrodiol; Estr-4-ene-3,17-diol, 17-ethynyl-, diacetate; Femulen; Cervicundin; ETHYNODIOL DIACETATE; MFCD00083326; 3β,17β-Diacetoxy-17α-ethynyl-4-estrene; EINECS 206-044-9; 19-Norpregn-4-en-20-yne-3,17-diyl diacetate; 17a-Ethynyl-4-estren-3b,17-diol diacetate; [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate; Luto-metrodiol; Ovulen 50; Ethynodiol (diacetate)
用途
医药；生命科学。
相关属性
基本信息物化属性
(4R,7S,10S,13R,16S,19R)-13-((1H-吲哚-3-基)甲基)-19-((R)-2-氨基-3-苯基丙酰胺基)-10-(4-氨基丁基)-16-苄基-N-((2R,3R)-1,3-二羟基丁-2-基)-7-((R)-1-羟乙基)-6,9,12,15,18-五氧代 -1,2-二硫杂-5,8,11,14,17-五氮杂环二十烷-4-羧酰胺 x乙酸盐
英文名称
Octreotide xAcetate
CAS号
79517-01-4
分子式
C₅₁H₇₀N₁₀O₁₂S₂
分子量
1079.29
中文别名
Octreotide Acetate; Sandostatin (TN); Octreotide acetate (USAN); 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-4-carboxamide, 10-(4-aminobutyl)-19-[[(2R)-2-amino-1-oxo-3-phenylpropyl]amino]-7-(1-hydroxyethyl)-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-16-(phenylmethyl)-, (4R,7S,10S,13R,16S,19R)-, acetate (1:1) (salt); Octreotide (acetate); (4R,7S,10S,13R,16S,19R)-10-(4-Aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxy-2-butanyl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate (1:1); Octreotide; Octreotide Acetate; SMS 201-995; Sandostatin LAR; (4R,7S,10S,13R,16S,19R)-10-(4-Aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxy-2-butanyl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide; Sandostatin; (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate (1:1); zacycloicosane-4-carboxamide acetate
用途
消化系统用药，主要用于治疗门脉高压引起的食管静脉曲张出血、肢端巨大症、消化道出血（如肝硬化、食管静脉曲张出血、消化性溃疡出血和应激性溃疡出血）、胰腺疾病（如重型急性胰腺炎、胰损伤或手术后胰腺瘘），预防胰腺手术后并发症；还用于胃肠道瘘管，消化系内分泌肿瘤（如肠血管活性肽瘤、胃泌素瘤、胰高血糖素瘤、异位ACTH综合征、类癌综合征），肢端肥大症，突眼性甲亢症，全结肠切除后持续性、顽固性腹泻和艾滋病相关性腹泻；鞘内注射可治疗癌性疼痛。
相关属性
基本信息物化属性
(4S,7S,10S,13S,19S,22S,25S,28S,34S,40S,43S,46S,49S)-25,40-双((1H-咪唑-5-基)甲基)-28-(2-氨基-2-氧代乙基)-49-((S)-2-((S)-2-((S)-2-((1S,4S,7S,10S,13S,16R,21R,24S,31R)-10-(3-氨基-3-氧代丙基)-7-(4-氨基丁基)-31- ((S)-3-羧基-2-((S)-1-((S)-4-甲基-2-((S)-1-((S)-5-氧代吡咯烷-2-羰基)吡咯烷-2-甲酰胺基)戊酰基)吡咯烷-2-甲酰胺基)丙酰胺基)-13-(3-胍基丙基)-4-((R)-1-羟乙基)-24-(羟甲基l)-3,6,9,12,15,23,26,32-八氧代-18,19,28,29-四硫杂-2,5,8,11,14,22,25,33-八氮杂双环[14.10.7]三十三烷-21-甲酰胺基)-5-胍基戊酰胺基)-4-甲基戊酰胺基)-3-(4-羟基苯基)丙酰胺基)-13-((S)-仲丁基)-4-氨基甲酰基-7-((R)-1-羟乙基)-10,43,46-三异丁基-2,19,22,34-四甲基-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-十五氧代-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-十五氮杂十五烷-52-酸
英文名称
(4S,7S,10S,13S,19S,22S,25S,28S,34S,40S,43S,46S,49S)-25,40-Bis((1H-imidazol-5-yl)methyl)-28-(2-amino-2-oxoethyl)-49-((S)-2-((S)-2-((S)-2-((1S,4S,7S,10S,13S,16R,21R,24S,31R)-10-(3-amino-3-oxopropyl)-7-(4-aminobutyl)-31-((S)-3-carboxy-2-((S)-1-((S)-4-methyl-2-((S)-1-((S)-5-oxopyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)propanamido)-13-(3-guanidinopropyl)-4-((R)-1-hydroxyethyl)-24-(hydroxymethyl)-3,6,9,12,15,23,26,32-octaoxo-18,19,28,29-tetrathia-2,5,8,11,14,22,25,33-octaazabicyclo[14.10.7]tritriacontane-21-carboxamido)-5-guanidinopentanamido)-4-methylpentanamido)-3-(4-hydroxyphenyl)propanamido)-13-((S)-sec-butyl)-4-carbamoyl-7-((R)-1-hydroxyethyl)-10,43,46-triisobutyl-2,19,22,34-tetramethyl-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-pentadecaoxo-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-pentadecaazadopentacontan-52-oic acid
CAS号
205640-90-0
分子式
C₁₅₂H₂₄₃N₄₇O₄₄S₄
分子量
3561.1
中文别名
Orexin A (human, rat, mouse); M.W. 3561.12 C152H243N47O44S4; Hypocretin 1; OREXINS OREXIN A HUMAN,RAT,MOUSE; Oroxin A; OREXIN A,BOVINE,HUMAN,MOUSE,RAT; Baicalin-7-glucoside; HYPOCRETIN; OREXIN A; PYR-PRO-LEU-PRO-ASP-CYS-CYS-ARG-GLN-LYS-THR-CYS-SER-CYS-ARG-LEU-TYR-GLU-LEU-LEU-HIS-GLY-ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-NH2(DISULFIDE BRIDGE: CYS6-CYS12,CYS7-CYS14); Pyr-PLPDCCRQKTCSCRLYELLHGAGNHAAGILTL-NH2(Disulfidebridge:6-12and7-14); Rat orexin A
用途
生命科学领域，作为Orexin A human, rat, mouse（33氨基酸兴奋性神经肽），特异性高亲和力激动OX1R，调节摄食行为，抗伤害和抗痛觉过敏；体外高亲和力结合OX1R（IC50 38 nM，EC50 34 nM）；体内实验（3-30 mg/kg i.v.）显著增加反应潜伏期，参考质量标准含外观、纯度等指标。
相关属性
基本信息物化属性
(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-二氟-11,17-二羟基-17-(2-羟基乙酰基)-10,13,16-三甲基-6,7,8,9,10,11,12,13,14,15,16,17-十二氢-3H-环戊烷并[a]菲-3-酮
英文名称
(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
CAS号
2135-17-3
分子式
C₂₂H₂₈F₂O₅
分子量
410.45
中文别名
Flumethasone; 6a-Fluorodexamethasone; (6α,11β,16α)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 6α-Fluorodexamethasone; 6α,9α-Difluoro-16α-methylprednisolone; Aniprime; Flumethasone; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluor-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-on; Fluvet; EINECS 218-370-9; flumetasone; 6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; Flucorticin; Anaprime; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; MFCD00056464; Flumethason; Cortexilar; 6a,9a-Difluoro-16a-methylprednisolone; Methagon; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
用途
作为中等强度局部用甾体药物，具有抗炎、抗过敏、血管收缩和抗组织增生等作用，常制备为复方氟米松软膏（含氟米松与水杨酸），用于治疗脂溢性皮炎、接触性皮炎等非感染性炎症性皮肤病，涂于患处每日1～2次，短期使用，长期使用可能有局部不良反应。
相关属性
基本信息物化属性
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-二氟-17-(((氟甲基)硫代)甲酰基)-11-羟基-10,13,16-三甲基-3-氧代-6,7,8,9,10,11,12,13,14,15,16,17-十二氢-3H-环戊并[a]菲-17-基丙酸酯
英文名称
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
CAS号
80474-14-2
分子式
C₂₅H₃₁F₃O₅S
分子量
500.57
中文别名
丙酸氟替卡松; Fluticasone propionate (JAN/USAN); Flonase; FLUNASE; Flovent DPI; Flutide N; Flixonase; (6α,11β,16α,17α)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propionate; Flixotide; flutide; MFCD08064194; Fluticasone propionate; (6α,11β,16α,17α)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate; (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(Fluoromethyl) Ester; flovent diskus; Zoflut; Cutivate; FLOVENT; Fluticasone (propionate)
用途
生命科学，是一种有效的局部抗炎激素，一种选择性的糖皮质激素受体 (glucocorticoid receptor) 激动剂；医药，为局部有效的皮质甾体药物，用于抗过敏反应，口服时经水解失活，能避免皮质激素的全身作用。
相关属性
基本信息物化属性
(6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-8b-(2-氯乙酰基)-6b-氟-7-羟基-6a,8a,10,10-四甲基-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-十四氢-4H-萘并[2',1':4,5]茚并[1,2-d][1,3]二氧戊环-4-酮
英文名称
(6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-8b-(2-Chloroacetyl)-6b-fluoro-7-hydroxy-6a,8a,10,10-tetramethyl-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
CAS号
3093-35-4
分子式
C₂₄H₃₂ClFO₅
分子量
454.96
中文别名
Halcinonide; Alcinonide; Halcort; 21-Chloro-9a-fluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-4-pregnene-3,20-dione; Halcimat; (11b,16a)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione; (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacétyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tétraméthyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tétradécahydro-2H-naphto[2',1':4,5]indéno[1,2-d][1,3]dioxol-2-one; UNII-SI86V6QNEG; Halciderm; Halog; (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(Chloracetyl)-4b-fluor-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; EINECS 221-439-6; halcinomide; Halcinonide; MFCD00866006; (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(Chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; UNII:SI86V6QNEG
用途
适用于接触性皮炎、特异性皮炎、苔癣化；面积不大的银屑病、苔癣、汗疹、生殖器萎缩硬化性苔癣、非寄生虫性痒疹、环型肉芽肿、盘状红斑狼疮、非面部的脂溢性皮炎、蕈样肉芽肿瘙痒症的对症治疗；昆虫叮咬，经特异性治疗后的寄生虫性痒疹的治疗；治疗牛皮癣有较好的疗效
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R)-13-乙基-17-乙炔基-3-(肟基)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊并[a]菲-17-基乙酸酯
英文名称
(8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-3-(hydroxyimino)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
CAS号
35189-28-7
分子式
C₂₃H₃₁NO₃
分子量
369.5
中文别名
Norgestimate; (3E,8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-3-(hydroxyimino)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate; (+)-13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one Oxime Acetate (Ester); d-17beta-acetoxy-13beta-ethyl-17alpha-ethinyl-gon-4en-3-one oxime; dexnorgestrelacetime; Norgestimat; Norgestimate; NORGESTIMATE,USP STANDARD; levonorgestrel acetate 3-oxime; (3E,8R,9S,10R,13S,14S,17R)-17-Ethinyl-13-ethyl-3-(hydroxyimino)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ylacetat; acétate de (3E,8R,9S,10R,13S,14S,17R)-13-éthyl-17-éthynyl-3-(hydroxyimino)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-1H-cyclopenta[a]phénanthrén-17-yle
用途
作为合成的孕激素类似物，是一种具有口服活性、高度选择性孕激素活性且雄激素作用小的孕激素，可用于口服避孕药；在体外研究中可转化为至少两种活性代谢物：左炔诺孕酮3-肟（去乙酰诺孕酯；诺孕曲明）和左炔诺孕酮
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R)-17-乙炔基-13-甲基-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊并[a]菲-17-醇
英文名称
(8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
CAS号
52-76-6
分子式
C₂₀H₂₈O
分子量
284.44
中文别名
利奈孕酮; exluten; exlution; org485-50; 19-Nor-4-pregnen-20-yn-17β-ol; LYNDIOL; MFCD00051135; orgametil; EINECS 200-151-4; 19-Norpregn-4-en-20-yn-17-ol; (17α)-17-ethynylestr-4-en-17-ol; ethinylestrenol; Exlutena; lynoestrenol; exluton; Lynestrenol; lynenol; exlutona
用途
医药领域应用；作为合成孕激素Lynestrenol（Ethinylestrenol），是孕酮受体激动剂，具有微弱雄激素和雌激素活性
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R)-17-乙炔基-13-甲基-3-氧代-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊并[a]菲-17-基乙酸酯
英文名称
(8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
CAS号
51-98-9
分子式
C₂₂H₂₈O₃
分子量
340.46
中文别名
醋酸炔诺酮; 17α-Ethinyl-19-nortestosterone acetate; NORLUTATE; 17α-Ethynyl-19-nortestosterone acetate; 19-Norethindrone acetate; 17β-Acetoxy-19-nor-17α-pregn-4-en-20-yn-3-one; (17α)-3-Oxo-19-norpregn-4-en-20-yn-17-yl acetate; 19-Nor-17α-pregn-4-en-20-yn-3-one, 17-hydroxy-, acetate; 17-α-Ethynyl-19-nortestosterone acetate; 17α-Ethinyl-19-nortestosterone-17β-acetate; Milligynon; MFCD04039850; 17α-Ethynyl-17β-acetoxy-19-norandrost-4-en-3-one; [(8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate; 17-Acetoxy-19-nor-17α-pregn-4-en-20-yn-3-one; Norethindrone acetate; Norethisterone acetate; Primolut-Nor; 17-Hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one acetate; EINECS 200-132-0; Norlutin A; 17-α-Ethinyl-19-nortestosterone-17-β-acetate; Norlutin acetate; 17α-Ethynyl-17-hydroxyestr-4-en-3-one acetate; Norethindrone 17-acetate; 17β-Hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one acetate; 19-Nor-17α-ethynyltestosterone Acetate; Estr-4-en-3-one, 17α-ethynyl-17-hydroxy-, acetate; 19-Nor-17α-pregn-4-en-20-yn-3-one, 17-hydroxy-, acetate (8CI); Aygestin; (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate; Norethisteron acetate; Norlutin-A
用途
孕激素类药，用于月经不调、子宫功能性出血、子宫内膜异位症等；可用于子宫内膜异位症研究，能缓解痛经和非周期性盆腔疼痛，改善出血和疼痛评分，对血脂有调节作用，且急性毒性低。
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R)-17-乙酰基-10,13-二甲基-3-氧代-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊并[a]菲-17-基己酸酯
英文名称
(8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hexanoate
CAS号
630-56-8
分子式
C₂₇H₄₀O₄
分子量
428.6
中文别名
17α-羟基孕酮己酸盐; Progesterone, 17-hydroxy-, hexanoate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate; 17-Hydroxypregn-4-ene-3,20-dione hexanoate; 3,20-Dioxopregn-4-en-1-yl hexanoate; hydroxyprogesterone caproate; EINECS 211-138-8; 17α-Caproyloxypregn-4-ene-3,20-dione; 17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione; Proluton depot; 17-α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone hexanoate; Delalutin; 3,20-Dioxopregn-4-en-17-ylhexanoat; Gesterol LA 250; Pharlon; Hexanoic acid, 3,20-dioxopregn-4-en-1-yl ester; Pregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate; (8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hexanoate; 17-α-Hexanoyloxypregn-4-ene-3,20-dione; 17-α-hydroxy-progesterone caproate; MFCD00072134; 17-α-Hydroxyprogesterone caproate; Teralutil; 17a-Hydroxyprogesterone caproate; Hexanoic acid, 3,20-dioxopregn-4-en-17-yl ester; 17a-Hydroxyprogesterone Hexanoate; 17α-Hydroxyprogesterone caproate; Proge; 3,20-Dioxopregn-4-en-17-yl hexanoate; 17-[(1-Oxohexyl)oxy]pregn-4-ene-3,20-dione
用途
用作孕激素类药，结合并激活核孕激素受体，抑制排卵、宫颈粘液和子宫内膜变化；与戊酸雌二醇配制成避孕针一号，注射一次可避孕一个月；在生殖系统研究中用于检测对第一代雄性生殖潜能的影响，胚胎期处理可降低成年大鼠血清睾酮水平，升高促卵泡激素和黄体化激素。
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R)-17-乙酰基-6,10,13-三甲基-16-亚甲基-3-氧代-2,3,8,9,10,11,12,13,14,15,16,17-十二氢-1H-环戊烯并[a]菲-17-基乙酸酯
英文名称
(8R,9S,10R,13S,14S,17R)-17-Acetyl-6,10,13-trimethyl-16-methylene-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
CAS号
2919-66-6
分子式
C₂₅H₃₂O₄
分子量
396.51
中文别名
Melengestrol Acetate; EINECS 220-859-7; 17-(acetyloxy)-6-methyl-16-methylenepregna-4,6-diene-3,20-dione; MGA; 6-methyl-16-methylidene-3,20-dioxopregna-4,6-dien-17-yl acetate; Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-16-methylene-, acetate; 17-Hydroxy-6-methyl-16-methylenepregna-4,6-diene-3,20-dione acetate; 6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate; 17- (acetyloxy)-6-methyl-16-methylenepregna-4,6-diene-3,20-dione; MFCD00072142; Melengestrol acetate; 17a-Acetoxy-6-methyl-16-methylene-4,6-pregnadiene-3,20-dione; 17α-Acetoxy-6-methyl-16-methylenepregna-4,6-diene-3,20-dione
用途
具有抗肿瘤及孕激素样活性;作为畜牧饲养的生长促进添加剂,改善饲养效率,加速牲畜体重增加
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R)-17-乙酰基-6-氯-10,13-二甲基-3-氧代-2,3,8,9,10,11,12,13,14,15,16,17-十二氢-1H-环戊烷并[a]菲-17-基乙酸酯
英文名称
(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
CAS号
302-22-7
分子式
C₂₃H₂₉ClO₄
分子量
404.93
中文别名
Chlormadinone acetate; Lormin; Normenon; ST 155; EINECS 206-118-0; Retex; Natrol; 17α-Acetoxy-6-chloropregna-4,6-diene-3,20-dione; 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate,Gestafortin,Matrol; MATROL; 6-Chloro-6-dehydro-17α-hydroxyprogesterone acetate; CMA; 6-Chloro-6-dehydro-17α-acetoxyprogesterone; 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione acetate; Gestafortin; Cero; 6-Chloro-3,20-dioxopregna-4,6-dien-17-yl acetate; 17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione; 6-chloro-17-hydroxypregna-4,6-diene-3,20-dione acetate; Chlordion; Chlormadinone acetate; Lutoral; rs1280; 17a-Acetoxy-6-chloro-6,7-dehydroprogesterone; 6-Chloro-6-dehydro-17a-hydroxyprogesterone Acetate; Verton; MFCD00056471; chlormadinone; Chloromadinone acetate; Chlormadinone (acetate)
用途
强效孕激素;具有抗雄激素和抗促性腺激素作用，半衰期约为34-38小时;口服-大鼠LD50:>10000毫克/公斤，口服-小鼠LD50:>15000毫克/公斤;热分解排出有毒氯化物烟雾;库房低温通风干燥;灭火剂为水、干粉、二氧化碳、泡沫
相关属性
基本信息物化属性
(8R,9S,10R,13S,14S,17R,E)-13-乙基-17-乙炔基-17-羟基-6,7,8,9,10,11,12,13,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-3(2H)-酮肟
英文名称
(8R,9S,10R,13S,14S,17R,E)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one oxime
CAS号
53016-31-2
分子式
C₂₁H₂₉NO₂
分子量
327.46
中文别名
Norgestimate metabolite Norelgestromin; UNII-R0TAY3X631; Levonorgestrel oxime; 17-Desacetyl Norgestimate; Norplant 3-oxime; 17-deacetylated norgestimate; Norelgestromin; (17alpha)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime (E)- and; D-Norgestrel 3-oxime; 17-Deacetylnorgestimate; 18-Methylnorethindrone oxime; Deacetylnorgestimate; Norgestimate metabolite Norelgestromin
用途
作为性激素属于孕激素类；抑制黄体生成素(LH)的释放并因此起抑制排卵的作用；相比前药诺孕酯或其代谢产物如3-酮诺孕酯和左炔诺孕酮，具有较低的雄激素作用；是诺孕酯(Norgestimate)的代谢物
相关属性
基本信息物化属性
(8R,9S,13S,14S,17S)-13-甲基-7,8,9,11,12,13,14,15,16,17-十氢-6H-环戊二烯并[a]菲-3,17-二基二丙酸酯
英文名称
(8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diyl dipropionate
CAS号
113-38-2
分子式
C₂₄H₃₂O₄
分子量
384.51
中文别名
Estradiol dipropionate; estradiol dipropionate; Diprostron; Agofollin; Diovocylin; Ovocyclin dipropionate; Dimenformon dipropionate; Progynon-DP; DTXSID8023000; NIG5418BXB; DTXCID303000; 3,17-dipropionyl-estra-1,3,5(10)-triene-3,17beta-diol; ESTRADIOL, DIPROPIONATE; RefChem:591259; (17 beta)-estra-1,3,5(10)-triene-3,17-diol, dipropanoate; (17beta)-Estra-1,3,5(10)-triene-3,17-diol Dipropanoate; 204-026-5; Diovocyclin; Estronex; Follicyclin P; Estroici; Nacyclyl; Ovocyclin-P; Oestradiol dipropionate; Endofollicolina D.P.; Estradiol 3,17-dipropionate; beta-Estradiol dipropionate; Oestradiol-3,17-dipropionate; 3,17beta-Estradiol dipropionate; Dipropionate D'oestradiol; MFCD00051146; Estradiol dipropionate [JAN]; 1,3,5(10)-Estratriene-3,17beta-diol dipropionate; Akrofolline; (17beta)-Estra-1,3,5(10)-triene-3,17-diol, dipropanoate; [(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate; Oestradiol Streuli; Agofollin [inj.]; Estradiol dipropionate (JAN); Oestradioli propionas; (17beta)-estra-1(10),2,4-triene-3,17-diyl dipropanoate; Progynon DP; (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diyl dipropionate; CCRIS 282; 17-beta-Estradiol dipropionate; 17-beta-Oestradiol dipropionate; 17-BETA-ESTRADIOL 3,17-DIPROPIONATE; 3,17-beta-Oestradiol dipropionate; Dipropionate d'oestradiol [French]; EINECS 204-026-5; UNII-NIG5418BXB; BRN 3223915; Ovahormon depot; Estradiol dipropionate [JAN:NF]; NCGC00159328-02; 17-Beta-Estradiol-3,17-Dipropionate; Estra-1,3,5(10)-triene-3,17-diol (17-beta)-dipropionate; 17α-ESTRADIOL 3,17-DIPROPIONATE; .beta.-Estradiol dipropionate; 4-06-00-06613 (Beilstein Handbook Reference); SCHEMBL348106; .beta.-Oestradiol dipropionate; Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, dipropanoate; orb1306011; CHEMBL1697791; SCHEMBL30595753; CHEBI:31560; 17-.beta.-Estradiol dipropionate; 17-.beta.-Oestradiol dipropionate; ESTRADIOL DIPROPIONATE [MI]; HY-B2245; Tox21_113111; .beta.-Estradiol 3,17-dipropionate; 17beta-Estradiol 3,17-Dipropionate; 3,17-.beta.-Estradiol dipropionate; LMST02010040; MSK011106; s5872; 3,17-.beta.-Oestradiol dipropionate; AKOS025311445
用途
用于女性更年期症状和低雌激素水平的激素治疗，也用于治疗妇科疾病；在体内研究中，用于卵巢切除小鼠的相关实验（如2μg per 100g皮下注射，联合绒毛膜促性腺激素处理）
相关属性
基本信息物化属性
(8R,9S,13S,14S,17S)-13-甲基-9,11,12,13,14,15,16,17-八氢-8H-环戊二烯并[a]菲-3,17-二醇
英文名称
(8R,9S,13S,14S,17S)-13-Methyl-9,11,12,13,14,15,16,17-octahydro-8H-cyclopenta[a]phenanthrene-3,17-diol
CAS号
7291-41-0
分子式
C₁₈H₂₂O₂
分子量
270.37
中文别名
雌二醇相关物质B标准品; oestra-1(10),2,4,6-tetraene-3,17beta-diol; 6,7-didehydro-17beta-estradiol; 6-dehydro-17beta-estradiol; (8R,9S,13S,14S,17S)-13-methyl-8,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol; 6,7-Dehydro Estradiol; Estra-1,3,5(10),6-tetraene-3,17-diol; Estra-1,3,5(10),6-tetraen-3,17beta-diol; 6-Dehydroestradiol
用途
化学合成。
相关属性
基本信息物化属性
(8S,10S,11S,13S,14S,16S,17R)-9-氯-11-羟基-10,13,16-三甲基-3-氧代-17-(2-(丙酰氧基)乙酰基)-6,7 ,8,9,10,11,12,13,14,15,16,17-十二氢-3H-环戊二烯并[a]菲-17基丙酸酯
英文名称
Beclometasone dipropionate
CAS号
5534-09-8
分子式
C₂₈H₃₇ClO₇
分子量
521.04
中文别名
丙酸倍氯米松; 9-Chloro-16-β-methyl-11-β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-Dipropionate; Viarex; Beconasol; Becloval; (11b,16b)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-[(propanoyloxy)acetyl]-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propanoate; Becodisks; Anceron; Vancenase AQ; propanoate de (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-triméthyl-3-oxo-17-[(propanoyloxy)acétyl]-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-17-yle; (11b,16b)-9-chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate; (11β,16β)-9-Chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate; EINECS 226-886-0; Beclomethasone dipropionate (USP); Beclomethasone dipropionate; Andion; MFCD00135613; (8S,9R,10S,11S,13S,14S,16S,17R)-9-Chlor-11-hydroxy-10,13,16-trimethyl-3-oxo-17-[(propanoyloxy)acetyl]-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-ylpropanoat; 9-Chloro-11b-hydroxy-16b-methylpregna-1,4-diene-3,20-dione 17,21-Dipropionate; Beclometasone dipropionate
用途
系强效外用糖皮质激素类药，具有抗炎、抗过敏和止痒等作用，能抑制支气管渗出物，消除支气管粘膜肿胀，解除支气管痉挛；用于治疗湿疹、过敏性皮炎、神经性皮炎、扁平苔藓、盘状红斑狼疮、掌跖脓疱病、接触性皮炎、局限性银屑病、皮肤瘙痒症等；气雾剂用于慢性或过敏性哮喘及过敏性鼻炎等；肾上腺皮质激素类药，可用于治疗各种炎症皮肤病。
相关属性
基本信息物化属性
(8S,13S,14S,17R)-17-乙炔基-13-甲基-7,8,12,13,14,15,16,17-八氢-6H-环戊二烯并[a]菲-3,17-二醇
英文名称
(8S,13S,14S,17R)-17-Ethynyl-13-methyl-7,8,12,13,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
CAS号
1231-96-5
分子式
C₂₀H₂₂O₂
分子量
294.39
中文别名
炔雌醇EP杂质B; 9,11-DEHYDRO ETHYLNYL ESTRADIOL (IMPURITY B); 19-NOR-17A-PREGNA-1,3,5(10),9(11)-TETRAEN-20-YNE-3,17-DIOL; 9,11-Dehydro Ethynyl Estradiol; DELTA-9(11)-ETHYNYLESTRADIOL
用途
化学合成。
相关属性
基本信息物化属性

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