- 英文名称
- Entecavir monohydrate
- 分子式
- C12H17N5O4
- 分子量
- 295.29
- 中文别名
- 恩替卡韦水合物; 恩替卡韦; 9-[(1S,3R,4S)-4-羟基-3-(羟甲基)-2-亚甲基环戊基]鸟嘌呤; 2-氨基-9-[(1S,3R,4S)-4-羟基-3-羟甲基-2-亚甲基环戊基]-1,9-二氢-6H-嘌呤-6-酮一水合物; 2-氨基-9-[(1S,3R,4S)-4-羟基-3-羟甲基-2-亚甲戊基]-1,9-氢-6-H-嘌呤-6-酮水合物; 2-氨基-9-[(1S,3R,4S)-4-羟基-3-羟甲基-2-亚甲戊基]-1,9-氢-6-H-嘌呤-6-酮一水合物; 2-氨基-9-((1S,3R,4S)-4-羟基-3-(羟甲基)-2-亚甲基环戊基)-1H-嘌呤-6(9H)-酮水合物; Entecavir hydrate; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate; 9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydrate; Entecavir (monohydrate); 2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one hydrate; 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one; entecavir
- 用途
- 恩替卡韦一水合物是抗乙肝病毒药物，适用于病毒复制活跃、血清转氨酶ALT持续升高或肝脏组织学显示有活动性病变的慢性成人乙型肝炎治疗，对拉米夫定耐药病毒株有效，长期应用耐药发生率低，可降低北美土拨鼠和鸭的肝炎病毒DNA水平，对HIV无临床相关活性。
