Recent advances in the development andcharacterizationof electrochemical and electricalbiosensorsfor small molecule neurotransmitters

Abstract Click to copy section link Section link copied! Neurotransmitters act as chemical messengers, determining human physiological and psychological function, and abnormal levels of neurotransmitters are related to conditions such as Parkinson’s and Alzheimer’s disease. Biologically and clinically relevant concentrations of neurotransmitters are usually very low (nM), so electrochemical and electronic sensors for neurotransmitter detection play an important role in achieving sensitive and selective detection. Additionally, these sensors have the distinct advantage to potentially be wireless, miniaturized, and multichannel, providing remarkable opportunities for implantable, long-term sensing capabilities unachievable by spectroscopic or chromatographic detection methods. In this article, we will focus on advances in the development and characterization of electrochemical and electronic sensors for neurotransmitters during the last five years, identifying how the field is progressing as well as critical knowledge gaps for sensor researchers. ACS Publications Copyright © 2023 American Chemical Society Subjects what are subjects Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Amines Electrochemical detection Electrodes Peptides and proteins Sensors Keywords what are keywords Article keywords are supplied by the authors and highlight key terms and topics

of the paper. electrochemistry biosensors biorecognition neurotransmitters small molecules