15397-12-3 2'-C-甲基腺苷

名称和标识

中文名: 2'-C-甲基腺苷
英文名: 2'-C-Methyladenosine
CAS号: 15397-12-3
分子式: C11H15N5O4
分子量: 281.27
中文别名: (2R,3R,4R,5R)-2-(6-氨基-9H-嘌呤-9-基)-5-(羟甲基)-3-甲基四氢呋喃-3,4-二醇; 2'-β-C-甲基腺苷
英文别名: 6-Amino-9-(2'-C-methyl-b-D-ribofuranosyl)purine; 2'-CMethyl-D-adenosine; Adenosine, 2'-C-methyl-; 2-(6-AMINOPURIN-9-YL)-5-(HYDROXYMETHYL)-3-METHYLOXOLANE-3,4-DIOL; (2R,3R,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; 2’-β-C-Methyladenosine; (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol; 2-(6-amino-purin-9-yl)-5-hydroxymethyl-3-methyl-tetrahydrofuran-3,4-diol; 2'-METHYLADENOSINE; 2'-C-methyl adenosine

用途与制备

丙型肝炎病毒(HCV)复制的抑制剂，抑制HCV复制子和NS5B催化的RNA合成，IC50值分别为0.3μM和1.9μM；有效抑制Leishmania guyanensis(Lgy)和Leishmania braziliensis中的LRV1

医药

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