7414-56-4 β,γ-亚甲基腺苷5'-三磷酸二钠盐

干冰运输。WGK Germany:3。存储类别:6.1C - 可燃，急性毒性 类别3（经皮、吸入、经口），眼部刺激 类别2，经皮刺激 类别2，特异性靶器官毒性-一次接触，类别3。

AMP-PCP disodium是一种ATP类似物，可以以Kd值为3.8μM来结合到Hsp90的N末端结构域；AMP-PCP disodium结合有利于Hsp90活性同型二聚体的形成；AMP-PCP binding favors the formation of the active homodimer of Hsp90 by enhancing the slow-motion featured conformational exchanges of those residues (A117-A141) within the lid segment (A111-G135) and around region；In total, 170 non-proline residues are identified for the triple-labeled Hsp90 bound with AMP-PCP

生命科学