- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- CYP1A2 inhibitor
- Yes
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- GI absorption
- High
- Log K p (skin permeation)
- -6.25 cm/s
- Log S (ESOL)
- -2.85
- LogP
- 1.07
- Molar Refractivity
- 57.53
- Num. H-bond acceptors
- 4.0
- Num. H-bond donors
- 0.0
- Num. rotatable bonds
- 2
- P-gp substrate
- No
- PSA
- 44.24 Ų
- Solubility
- 0.314 mg/ml ; 0.0014 mol/l
- Synthetic accessibility
- 2.09
- 储存条件
- 2-8°C，保存于惰性气体中
- 外观
- 固体，粘黄色
- 密度
- 1.3±0.1 g/cm³
- 折射率
- 1.605
- 沸点
- 412.0±40.0 °C (760 mmHg)
- 溶解度
- 可溶于二氯甲烷、甲醇
- 熔点
- 36.7 °C
- 精确质量
- 224.035248
- 蒸汽压
- 0.0±0.9 mmHg (25 °C)
- 酸度系数(pKa)
- 1.98±0.30 (Predicted)
- 闪点
- 203.0±27.3 °C
