676560-15-9 4-((叔丁基二甲基甲硅烷基)氧基)环己烷羧酸乙酯

合成路线 1（1. 合成：676560-15-9）

• 产率：100%
• 合成条件：With 1H-imidazole In DMF (N,N-dimethyl-formamide) at 35℃; for 12 h;
• 实验步骤：向叔丁基二甲基甲硅烷基氯（10.6g，70mmol）和咪唑（9.9g，145mmol）的DMF（20mL）溶液中加入4-羟基-环己烷羧酸乙酯（9.4mL，58mmol）。将混合物在35℃下搅拌12小时，用EtOAc（100mL）稀释，用H₂O（3次）洗涤，干燥（Na₂SO₄）并浓缩。以定量收率（16.6g）分离所得白色固体，不经纯化用于下一步骤。
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