86559-73-1 脂质X

名称和标识

中文名: 脂质X
英文名: lipid X
CAS号: 86559-73-1
分子式: C34H66NO12P
分子量: 711.86
中文别名: DNA-PK抑制剂(COMPOUND 401); 化合物 LIPID X
英文别名: 2,3-Di(3-hydroxymyristoyl)glucosamine 1-phosphate; 2-[[(3R)-3-Hydroxymyristoyl]amino]-2-deoxy-3-O-[(3R)-3-hydroxymyristoyl]α-D-glucopyranose 1-phosphoric acid; Compound 401; N,3-O-Bis[(R)-3-hydroxytetradecanoyl]-α-D-glucosamine 1-phosphoric acid; Phosphoric acid dihydrogen [2-deoxy-3-O-[(R)-3-hydroxytetradecanoyl]-2-[(R)-3-hydroxytetradecanoylamino]-α-D-glucopyranosyl] ester; α-D-Glucopyranose, 2-deoxy-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate) 3-[(3R)-3-hydroxytetradecanoate]; (2R,3S,4R,5R,6R)-3-Hydroxy-2-(hydroxymethyl)-5-((R)-3-hydroxytetradecanamido)-6-(phosphonooxy)tetrahydro-2H-pyran-4-yl (R)-3-hydroxytetradecanoate

用途与制备

Lipid X是Lipid A的新型单糖前体，Lipid A是革兰氏阴性内毒素的活性部分；对小鼠和绵羊的内毒素具有保护作用；对小鼠内具有威胁生命的革兰氏阴性菌感染有着保护作用。

医药

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