81381-50-2 (D-ALA4)-P物质(4-11)

名称和标识

中文名: (D-ALA4)-P物质(4-11)
英文名: [D-Ala4]-Substance P (4-11)
CAS号: 81381-50-2
分子式: C44H65N11O10S
分子量: 940.12
中文别名: D-ALA4]-神经肽P物质4-11; P物质肽[DALA4] SUBSTANCE P(4-11); D-丙氨酸4]P物质(4-11)
英文别名: D-Alanyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide; Substance P,fragment 4-11,(D-Ala4); D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2; H-D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2; SUBSTANCE P OCTAPEPTIDE D-ALA-4-FRAGMENT 4-11; (2S)-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-[[(2R)-2-aminopropanoyl]amino]pentanediamide; Substance P,1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-D-alanine-; Substance P,1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-D-alanine- (9CI)

用途与制备

(D-ALA4)-SUBSTANCE P (4-11)是Substance P的类似物，可抑制125I-Bolton Hunter偶联的Eledoisin（IC50为0.5μM）和125I-Bolton Hunter偶联的Substance P（IC50为0.15μM）与大鼠大脑皮层膜的结合。

医药

词条详情加载中…