- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- CYP1A2 inhibitor
- Yes
- CYP2C19 inhibitor
- Yes
- CYP2C9 inhibitor
- Yes
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- Yes
- Fraction Csp3
- 0.15
- GI absorption
- High
- Log K p (skin permeation)
- -5.11 cm/s
- Log S (Ali)
- -5.57
- Log S (ESOL)
- -4.81
- Log S (SILICOS-IT)
- -4.65
- LogP
- 5.99
- Molar Refractivity
- 94.42
- Num. H-bond acceptors
- 4.0
- Num. H-bond donors
- 2.0
- Num. arom. heavy atoms
- 12
- Num. heavy atoms
- 24
- Num. rotatable bonds
- 3
- P-gp substrate
- No
- 储存条件
- 4°C, away from moisture and light
- 外观
- 固体，颜色为浅黄至黄色
- 密度
- 1.3±0.1 g/cm³
- 折射率
- 1.651
- 拓扑分子极性表面积
- 66.76 Ų
- 水溶解性
- 0.00495 mg/ml ; 0.0000153 mol/l
- 沸点
- 535.1±50.0 °C (760 mmHg)
- 精确质量
- 322.120514
- 蒸汽压
- 0.0±1.5 mmHg (25 °C)
- 酸度系数(pKa)
- 7.13±0.40 (Predicted)
- 闪点
- 193.7±23.6 °C
