4753-04-2 2'-氯-2'-脱氧尿苷

名称和标识

中文名: 2'-氯-2'-脱氧尿苷
英文名: 2'-chloro-2'-deoxyuridine
CAS号: 4753-04-2
分子式: C9H11ClN2O5
分子量: 262.65
中文别名: 1-((2R,3R,4R,5R)-3-氯-4-羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮; 2'-CL-DU
英文别名: 1-((2R,3R,4R,5R)-3-Chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2-CHLORO-2-DEOXYURIDINE; 2'-Chlor-2'-deoxy-uridin; 2'-chloro-dU; 2'-Chlor-2'-desoxyuridin; 2'-Chloro-2'-deoxy-uridin; NSC 526746; Uridine, 2'-chloro-2'-deoxy-; 1-[(2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

用途与制备

作为嘌呤核苷类似物，具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤；通过抑制DNA合成、诱导细胞凋亡发挥抗癌作用

医药

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