158442-41-2 Z-异亮氨酰-叔丁基谷氨酰-丙氨酸-亮氨酸缩醛

名称和标识

中文名: Z-异亮氨酰-叔丁基谷氨酰-丙氨酸-亮氨酸缩醛
英文名: Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde
CAS号: 158442-41-2
分子式: C32H50N4O8
分子量: 618.76
中文别名: 化合物PSI; PSI(蛋白酶体抑制剂); PSI
英文别名: N-[(Phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-tert-butylester-N-[(1S)-1-formyl-3-methylbutyl]-L-alaninamide; PROTEASOME INHIBITOR I; tert-Butyl (4S)-4-{[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-methylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-methyl-1-oxopentan-2-yl]amino}-1-oxopropan-2-yl]amino}-5-oxopentanoate; 2-Methyl-2-propanyl (4S)-4-{[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-methylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-methyl-1-oxo-2-pentanyl]amino}-1-oxo-2-propanyl]amino}-5-oxopentanoate; PSI; Proteasome Inhibitor 1; Z-Ile-Glu(O-t-butyl)-Ala-Leucinal; IEAL; PSI peptide; Z-Ile-Glu(OBut)-Ala-Leu-H; Z-Ile-Glu(OBut)-Ala-Leu-al; benzyloxycarbonyl-isoleucyl-glutamyl(O-tert-butyl)-alanyl-leucinal; CARBOBENZOXY-L-ISOLEUCYL-GAMMA-T-BUTYL-L-GLUTAMYL-L-ALANYL-L-LEUCINAL; BENZYLOXYCARBONYL-L-ISOLEUCYL-[(2S)-2-AMINO-4-(T-BUTYLOXYCARBONYL)BUTANOYL]-L-ALANYL-L-LEUCINAL; PROTEASOME INHIBITOR I (ALDEHYDE); PROTEASOME INHIBITOR PSI; N-CBZ-ILE-GLU(O-T-BUTYL)-ALA-LEUCINAL; Z-IE(OTBU)AL-CHO

安全说明

运输方式：冰袋运输。危险性质：非危险化学品。WGK Germany:3，存储类别为10 - 可燃性液体。

用途与制备

化学合成；作为有效的蛋白酶体抑制剂，抑制原发性渗出性淋巴瘤（PEL）细胞的增殖，具有研究卡波济氏肉瘤相关疱疹病毒（KSHV）感染和KSHV相关淋巴瘤的潜力。

医药

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