1454619-14-7 8-((3,5-二氯苯基)硫基)-9-(3-(异丙基氨基)丙基)-9H-嘌呤-6-胺

运输信息：冰袋运输。危险描述：非危险化学品。

PU-WS13 is a selective Grp94 inhibitor (EC50 0.22 μM), slightly suppressing Hsp90α (27.3 μM), Hsp90β (41.8 μM), and Trap-1 (7.3 μM). It shows no toxicity to nonmalignant cells at 2.5-20 μM, disrupts HER2 circular architecture in SKBr3 cells, and induces apoptosis in HER2-overexpressing breast cancer cells.

医药