1438391-30-0 3-(3-(2-(哌啶-1-基)乙氧基)苯基)-5-(1H-1,2,4-三唑-5-基)-1H-吲唑盐酸盐

名称和标识

中文名: 3-(3-(2-(哌啶-1-基)乙氧基)苯基)-5-(1H-1,2,4-三唑-5-基)-1H-吲唑盐酸盐
英文名: CC-401 hydrochloride
CAS号: 1438391-30-0
分子式: C22H25ClN6O
分子量: 424.93
中文别名: 3-[3-[2-(1-哌啶基)乙氧基]苯基]-5-(1H-1,2,4-三唑-5-基)-1H-吲唑盐酸盐; JNK抑制剂(CC-401盐酸盐); CC-401盐酸盐; 化合物CC-401盐酸盐
英文别名: CC401 HCl; CC-401 (hydrochloride); 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride (1:1); CC 401 HYDROCHLORIDE; CC401 HYDROCHLORIDE; 3-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-3-yl)-1H-indazole hydrochloride; 3-(3-(2-(Piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride; 1H-Indazole, 3-[3-[2-(1-piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-, hydrochloride (1:1); 3-{3-[2-(1-Piperidinyl)ethoxy]phenyl}-5-(1H-1,2,4-triazol-3-yl)-1H-indazole hydrochloride (1:1); 3-[3-(2-piperidin-1-ylethoxy)phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride

安全说明

运输方式为冰袋运输。危险性质：非危险化学品。WGK Germany: WGK 3。海关编码: 2933399990。存储类别: 11 - 可燃固体

用途与制备

化学合成；作为有效的JNK抑制剂，对JNK的选择性至少是其他相关激酶的40倍，用于体外和体内研究，如抑制c-Jun磷酸化、减缓蛋白尿进展、预防肾损伤等。

医药