1402152-13-9 库潘尼西二盐酸盐

运输方式：冰袋运输。危险描述：吞食致命；可能损害未出生婴儿、怀疑损害生育力；长期或反复接触损害器官；对水生生物有长期毒性。防护措施：P203、P260、P270、P280、P301+P316、P318、P321、P330、P391、P405、P501。危险类别：急性毒性2级、生殖毒性1B级、特定目标器官毒性（反复接触）1级、水生环境危害慢性1级。

Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an effective, selective, and ATP-competitive pan class I PI3K inhibitor, with IC50 values of 0.5 nM (PI3Kα), 0.7 nM (PI3Kδ), 3.7 nM (PI3Kβ), and 6.4 nM (PI3Kγ). It has >2000-fold selectivity over other kinases except mTOR, and exhibits excellent antitumor activity, primarily used in life sciences for research and potential clinical applications.

生命科学; 抗肿瘤药物研发