174575-17-8 (S)-α-氨基-2'-氯-5-(膦酰基甲基)-[1,1'-联苯]-3-丙酸
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安全说明
运输方式:冰袋运输。危险描述:非危险化学品(但GHS分类显示具有皮肤刺激(2级)、严重眼刺激(2级)、呼吸道刺激(单次暴露)的危害。防护措施:P261、P264等警示和预防措施。
用途与制备
SDZ 220-581 is used in life sciences as an orally bioavailable, competitive NMDA receptor antagonist (pKi 7.7). It dose-dependently protects male OF-l mice (18-26 g) against maximal electroshock seizures (MES) when administered orally at 3.2-32 mg/kg for 24 hours, with rapid onset and long duration of action.
生命科学; 医药