1776112-90-3 N-((3R,4R)-4-氟-1-(6-((3-甲氧基-1-甲基-1H-吡唑-4-基)氨基)-9-甲基-9H-嘌呤-2-基)吡咯烷-3-基)丙烯酰胺
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安全说明
GHS分类:警告,H373(100%):长期或反复接触可能损害器官(特定目标器官毒性,反复接触);预防措施代码P260、P319、P501;危险类别STOT RE 2(100%)。德国WGK:3;存储类别:11 - 可燃固体。
用途与制备
Mavelertinib is a selective, oral, irreversible EGFR tyrosine kinase inhibitor (EGFR TKI) with IC50 values of 5, 4, 12, and 3 nM for Del, L858R, T790M/L858R, and T790M/Del mutations respectively. It is used in non-small cell lung cancer (NSCLC) research.
医药