128219-84-1 5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-O-甲基肌苷

名称和标识

中文名: 5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-O-甲基肌苷
英文名: 5'-O-(Dimethoxytrityl)-2'-O-methylinosine
CAS号: 128219-84-1
分子式: C32H32N4O7
分子量: 584.62
中文别名: 9-((2R,3R,4R,5R)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-羟基-3-甲氧基四氢呋喃-2-基)-9H-嘌呤-6-醇; 5-O-(二甲氧基三苯甲游基)-2-o-甲基肌苷; 5'-O-(二甲氧基三苯甲基)-2'-O-甲基肌苷
英文别名: 9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-ol; 5'-O-DMT-2'-O-methylinosine; 5'-O-Dmt-2'-O-methyl-inosine; 9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-1H-purin-6-one; 9-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxy-3-methoxyoxolan-2-yl]-9H-purin-6-ol; 5'-O-DMT-2'-O-methyl-D-inosine; 5'-O-Dimethoxytrityl-2'-O-methylinosine; Inosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-Methyl- (9CI)

用途与制备

5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-O-甲基肌苷是一种嘌呤核苷类似物，具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤，其抗癌机制依赖于抑制DNA合成，诱导细胞凋亡等。

医药

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