101236-50-4 苦参醇 L

中文名称: 苦参醇 L
英文名称: Kushenol L
CAS号
分子式: C₂₅H₂₈O₇
分子量: 440.49
更新日期: 2026-06-23

名称和标识

中文名: 苦参醇 L
英文名: Kushenol L
CAS号: 101236-50-4
分子式: C25H28O7
分子量: 440.49
中文别名: (2R,3R)-2-(2,4-二羟基苯基)-3,5,7-三羟基-6,8-双(3-甲基丁-2-烯-1-基)苯并吡喃-4-酮
英文别名: (2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one; (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one; (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one; KushenolL; (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-1-benzopyran-4-one; (2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-enyl)chroman-4-one; 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-, (2R,3R)-

物化属性

LogP: 5.88
PSA: 127.45 Å²
XLogP3-AA: 5.3
pKa: 8.04±0.60 (Predicted)
储存条件: 室温
分子量: 440.5 g/mol
外观: 粉末或水晶状
密度: 1.3±0.1 g/cm³
折射率: 1.650
沸点: 715.7±60.0 °C (760 mmHg)
溶解度: 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等
精确质量: 440.18350323
蒸汽压: 0.0±2.4 mmHg (25°C)
闪点: 244.7±26.4 °C

安全信息

安全说明

运输信息：冰袋运输。危险描述：非危险化学品。

生产及用途

用途与制备

Kushenol L is a major component of Sophora flavescens Ait's ethanol extract, used in life sciences and traditional Chinese medicine. It exhibits anti-diabetic activity and has been studied for its pharmacokinetics in adult male Sprague-Dawley rats (300g) with 1mg/kg oral administration: T₁/₂=2.26 hours, Cmax=24.17μg/L, AUC=54035μg/h•L.

医药; 生命科学; 中草药成分

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