110764-78-8 (2R,3R,4R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-甲氧基四氢呋喃-3-基 (2-氰乙基)二异丙基亚磷酰胺

中文名称: (2R,3R,4R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-甲氧基四氢呋喃-3-基 (2-氰乙基)二异丙基亚磷酰胺
英文名称: (2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CAS号
分子式: C₄₇H₅₄N₅O₉P
分子量: 863.93
更新日期: 2026-06-23

名称和标识

中文名: (2R,3R,4R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-甲氧基四氢呋喃-3-基 (2-氰乙基)二异丙基亚磷酰胺
英文名: (2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CAS号: 110764-78-8
分子式: C47H54N5O9P
分子量: 863.93
中文别名: DMT-2’-O-甲基-rC亚磷酰胺; 2-OME-BZ-C 亚磷酰胺单体; 2'-OMe-Bz-C亚磷酰胺单体; 2'-OME-BZ-C 亚磷酰胺单体; 2'-OMe-C(Bz) 亚磷酰胺单体; N-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-O-甲基胞苷 3'-[2-氰基乙基二异丙基氨基膦酸酯]; N4-苯甲酰基-5'-O-DMT-2'-甲氧基胞苷-氰乙氧基亚磷酰胺; 2'-OME-C(BZ)亚磷酰胺单体; 2'-OME-BZ-C-CE-亚磷酰胺
英文别名: DMT-2’-O-methyl-rC(Bz) Phosphoramidite; N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide; 2'-OMe-Bz-C Phosphoramidite; 2'-OMe-Bz-CPhosphoramidite; N-Benzoyl-5'-O-[Bis(4-Methoxyphenyl)(Phenyl)Methyl]-3'-O-[(2-Cyanoethoxy)(Diisopropylamino)Phosphino]-2'-O-Methylcytidine; 2'-O-Me-C(Bz) Phosphoramidite; N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite; N4-Bz-5'-O-DMTr-2'-O-Me-cytidine-3'-CED-phosphoramidite; N-{1-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-methoxyoxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide; 5'-O-DMTr-2'-O-Me-C(Bz)-CE Phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-O-methylcytidine; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl diisopropylphosphoramidite); 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine-3'-CE-Phosphoramidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methycytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-DMT-N4-Benzoyl-2'-O-methylcytidine 3'-CE phosphoramidite; Bz-2'-OMe-C Phosphoramidite

物化属性

LogP: 7.92928
PSA: 172.71000 Å²
XLogP3-AA: 6.4
储存条件: 2-8°C
分子量: 863.9 g/mol
外观: 白色至淡黄色固体，对热和湿敏感
形态: 固体
溶解度: DMSO：100 mg/mL（115.75 mM；需要超声波）
精确质量: 863.36591531 Da
酸度系数: 8.57±0.20 (Predicted)

安全信息

安全说明

干冰运输相关信息中，危险性质被描述为非危险化学品，海关编码为29349990

生产及用途

用途与制备

2'-OME-BZ-C 亚磷酰胺单体是一种修饰过的亚磷酰胺单体，可用于寡核苷酸的合成。

化学合成；生命科学

词条详情加载中…

110764-78-8 (2R,3R,4R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-甲氧基四氢呋喃-3-基 (2-氰乙基)二异丙基亚磷酰胺

中文名称

(2R,3R,4R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-甲氧基四氢呋喃-3-基 (2-氰乙基)二异丙基亚磷酰胺

英文名称

(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS号

分子式

C₄₇H₅₄N₅O₉P

分子量

863.93

更新日期

2026-06-23