化学合成
化学合成
合成路线 1（1. 合成：949-99-5）
产率：95.2%
合成条件：Stage #1: With sulfuric acid; nitric acid In water at 20℃; Stage #2: With sodium hydroxide In water
实验步骤：制备方法：将L-苯丙氨酸（16.5g，100mmol）溶于85％H 2 SO 4（50ml）中。 在搅拌下向混合物中滴加浓HNO 3和浓H 2 SO 4（V / V = 1.4 / 1.1）的混合酸，将其预先制备并冷却至室温。 将反应混合物在室温下搅拌5小时。 用40％NaOH将反应溶液的pH调节至2-3。 获得大量沉淀物。 过滤沉淀物，用水洗涤直至pH为中性，并在减压下干燥，得到4-硝基-L-苯丙氨酸（20g，95.2％）。
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