化学合成。
化学合成
合成路线 1（1. 合成：1224844-66-9）
产率：89.5%
合成条件：With dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium cesium chloride; potassium acetate In 1,4-dioxane for 3 h; Inert atmosphere; Reflux
实验步骤：具体操作：将127g化合物4,182g双硼酸酯，45g 1,1'-双（二苯基膦基）二茂铁二氯化钯（dppf氯化铯）和180g乙酸钾加入2L 1,4-二恶烷中， 将混合物在氮气下回流3小时，冷却至室温，过滤并浓缩，得到粗化合物5.将粗化合物5溶于500ml石油醚中并搅拌1小时。 ，过滤，在50℃下真空干燥，得到110g化合物6，产率89.5％。
参考文献：
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