靶点
Target: fungi, yeast and gram-positive bacteria
体外研究
Pyrrolnitrin (0-100 μg/ml) shows antibiotic activities against various bacteria and fungi with different MIC values. It against
Staphylococcus aureus
,
Mycobacterium
,
Bacillus subtillis
,
Candida albicans
,
Aspergillus niger
, and
Trichophyton rubrum
with MIC values of 50 μg/ml, 100 μg/ml, 0.78 μg/ml, 10 μg/ml, 12.5 μg/ml, and 1 μg/ml, respectively.
Pyrrolnitrin (0-100 μg/ml) exhibits antimicrobial effect in a microtitre plate assay. It against
Arthrobacter oxydans
ATCC 14358,
Bacillus coagulans
ATCC 7050,
Bacillus licheniformis
ATCC 14580,
Bacillus subtilis
ATCC 6051, and
Bacillus thuringiensis
ATCC 10792 with MIC of 6.25 μg/ml.
