4-氯-2-(苯基炔基)苯胺主要应用于医药和农药领域（具体用途未详细说明）。
医药; 农药
合成路线 1（1. 合成：928782-97-2）
产率：80%
合成条件：With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; Inert atmosphere; Schlenk technique
实验步骤：一般步骤：在典型的反应中，将PdCl 2（PPh 3）2（88mg，0.125mmol），CuI（24mg，0.125mmol）和THF（5ml）置于烘箱干燥的2颈RB烧瓶中。 向该悬浮液中加入2-碘苯胺（5.47mg，2.5mmol）和三乙胺（702μl，5.0mmol）。 通过用氩气鼓泡将反应混合物脱气15分钟。 然后加入苯乙炔（300μl，2.75mmol），并将反应混合物在室温下搅拌。 在完全消耗2-碘苯胺（约2小时，通过TLC）后，将反应混合物通过硅藻土过滤，并将溶剂旋转蒸发，得到粗产物，将其通过硅胶（60-120目）柱色谱法纯化。 乙酸乙酯/己烷（1：9，v / v）作为洗脱剂，得到纯的2-苯基乙炔基苯胺，2a（400mg，83％）。
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