1011-84-3 4-硝基氯苯甲醛肟

危险性质：非危险化学品

化学合成。

化学合成

合成路线 1（1. 合成：1011-84-3）

产率：100% 合成条件：With N-chloro-succinimide In N,N-dimethyl-formamide at 0 - 20℃; 实验步骤：化合物YD-032Y的合成将YZ（087mg，5.3mmol）溶于无水二甲基甲酰胺（4.6mL）中，将溶液冷却至0℃。 在搅拌下分批加入N-氯代琥珀酰亚胺（800mg，6.0mmol）。 移去冷却浴，将所得混合物在室温下搅拌4小时。 完成后，加入冰水（20mL），用乙醚萃取所得混合物。 将有机层用水洗涤3次，用饱和食盐水洗涤一次，用硫酸镁干燥。 过滤后除去溶剂，得到白色固体YD-032（1.064g，100％）。 1H NMR（400MHz，CDCl3），δ8.37（s，1H，-OH），8.27（d，J = 8.8Hz，2H，Ar-H），8.04（d，J = 8.8Hz，2H，AR-H）。 参考文献：

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