化学合成。
医药
合成路线 1（1. 合成：25392-41-0）
产率：91%
合成条件：at 90℃; for 5 h;
实验步骤：一般步骤：将苯酚（1.0mmol），β-酮酯（1.5mmol）和MNESA（0.075g）的混合物在90℃下在圆底烧瓶中搅拌一段时间。 通过TLC确认反应完成后，将反应混合物冷却至室温，并使用外部磁场Some场将催化剂与反应混合物分离。 然后将水加入到反应混合物中，并使用EtOAc（29×10mL）萃取产物。 将合并的有机层用无水Na 2 SO 4干燥，过滤并真空浓缩，得到粗产物。 为了进一步纯化，通过在乙醇中重结晶纯化粗产物，以获得所需的纯度。
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