化学合成。
医药
合成路线 1（1. 合成：571189-49-6）
产率：99%
合成条件：for 5 h;
实验步骤：将1-甲基-4-（6-硝基 - 吡啶-3-基） - 哌嗪（1.11g，5.02mmol）和10％Pd / C（110mg）的MeOH（15mL）溶液搅拌5小时并过滤。 浓缩滤液，得到951mg（99％收率）黄色固体，其不经进一步纯化而使用。 1H NMR（CDCl3）：δ7.78（d，1H，J = 3.0Hz），7.18（dd，1H，J = 3.0,8.9Hz），6.48（d，1H，J = 8.9Hz），3.08（dd，4H） ，J = 4.9,4.9Hz），2.61（dd，4H，J = 4.9,4.9Hz），2.37（s，3H）。
参考文献：
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