化学合成。
化学合成
合成路线 1（1. 合成：7627-44-3）
产率：100%
合成条件：With sodium iodide In acetone at 20℃; for 0.58 h; Heating / reflux
实验步骤：将2,4-二氯-5-氯甲基 - 嘧啶（10g，50.6mmol），碘化钠（7.69g，51.3mmol）的丙酮（60ml）混合物在室温下搅拌20分钟，然后回流15分钟。分钟。 使反应冷却至室温，然后过滤固体并用丙酮洗涤。 浓缩滤液，得到2,4-二氯-5-碘甲基 - 嘧啶，为浅黄色固体（14.6g，100％）; 1H NMR 400MHz（CDCl3）？ 8.54（s，IH），4.33（s，2H）; MS m / z 288.9（M + 1）。
参考文献：
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