作为医药中间体或活性成分,用于相关药物研发与合成。
医药
合成路线 1(1. 合成:75476-86-7)
产率:100%
合成条件:With sodium tetrahydroborate In ethanol at 10 - 20℃; for 3 h;
实验步骤:168.8g compd。 在瓶子的反应过程中加入6和650ml乙醇。 接下来,水温低于10°C,少量添加NaBH445g。 接下来,将温度升至室温,将反应溶液连续搅拌3小时。 反应完成后,除去乙醇,然后依次加入10ml HCl 450ml的水解。 用二氯甲烷萃取混合物,然后用水洗涤,干燥,然后除去溶剂,170g化合物。 其中产率为100%(珊瑚石固体)。 以下关系的路径的反应。
参考文献:
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