- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- Brenk
- 0.0 alert
- CYP1A2 inhibitor
- Yes
- CYP2C19 inhibitor
- Yes
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- Yes
- CYP3A4 inhibitor
- Yes
- Egan
- 0.0
- Fraction Csp3
- 0.14
- GI absorption
- High
- Leadlikeness
- 2.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -4.95 cm/s
- Log S (Ali)
- -3.94
- Log S (ESOL)
- -4.03
- Log S (SILICOS-IT)
- -5.48
- LogP
- 4.09
- Molar Refractivity
- 67.26
- Muegge
- 0.0
- Num. H-bond acceptors
- 1.0
- Num. H-bond donors
- 1.0
- Num. arom. heavy atoms
- 13
- Num. heavy atoms
- 16
- Num. rotatable bonds
- 1
- P-gp substrate
- Yes
- PAINS
- 0.0 alert
- PSA
- 25.02 Ų
- Synthetic accessibility
- 1.67
- Veber
- 0.0
- 外观
- White to off-white, 固体
- 密度
- 1.2±0.1 g/cm³
- 折射率
- 1.697
- 水溶解性
- water: slightly soluble
- 沸点
- 409.0±25.0 °C (760 mmHg)
- 熔点
- 51-53 °C
- 精确质量
- 211.099716
- 蒸汽压
- 0.0±0.9 mmHg (25 °C)
- 闪点
- 148.0±13.4 °C
