2373-89-9 4,4'-二甲氧基查耳酮

海关编码:29145090

• 生物活性 4,4'-Dimethoxychalcone 可从植物当归中分离得到，是一种天然自噬 (autophagy) 诱导剂，具有抗衰老活性。
• 靶点 Autophagy
• 体内研究 The flavonoid 4,4'-Dimethoxychalcone acts as an anti-ageing compound with cardioprotective effects in mice and the potential to promote longevity across species. 4,4'-Dimethoxychalcone (100 mg/kg; intraperitoneally) efficiently triggered autophagic flux in the heart and liver from wild type (WT) C57BL/6 mice. Animal Model: 6-week-old male wild type C57BL/6 or Atg4b -/- mice Dosage: 100 mg/kg Administration: Injected intraperitoneally with a single Result: Triggered autophagic flux in the heart and liver.

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