体内研究
The flavonoid 4,4'-Dimethoxychalcone acts as an anti-ageing compound with cardioprotective effects in mice and the potential to promote longevity across species.
4,4'-Dimethoxychalcone (100 mg/kg; intraperitoneally) efficiently triggered autophagic flux in the heart and liver from wild type (WT) C57BL/6 mice.
Animal Model:
6-week-old male wild type C57BL/6 or Atg4b
-/-
mice
Dosage:
100 mg/kg
Administration:
Injected intraperitoneally with a single
Result:
Triggered autophagic flux in the heart and liver.