26117-28-2 N-乙酰基-D-半胱氨酸

名称和标识

中文名: N-乙酰基-D-半胱氨酸
英文名: N-acetyl-D-cysteine
CAS号: 26117-28-2
分子式: C5H9NO3S
分子量: 163.19
中文别名: 乙酰半胱氨酸杂质F; 乙酰半胱氨酸杂质9; 乙酰基半胱氨酸杂质5; 乙酰半胱氨酸杂质5; 乙酰半胱氨酸杂质异构体; N-乙酰-D-半胱氨酸
英文别名: Cysteine, N-acetyl-, D- (8CI); D-Cysteine, N-acetyl-; D-N-Acetylcysteine; N-Acetyl-(S)-cysteine; (S)-2-(Acetylamino)-3-mercaptopropanoic acid; (S)-2-Acetylamino-3-mercaptopropionic acid; acetylcysteine; N-Acetylcysteine; N-acetyl-3-mercaptoalanine; (2S)-2-acetamido-3-sulfanylpropanoic acid; D-Cysteine,N-acetyl

用途与制备

生物活性 N-Acetyl-D-cysteine 具有抗氧化活性，通过与巯基反应清除 ROS，但不能进入谷胱甘肽代谢途径。
体外研究 N-Acetyl-D-cysteine (20 mM; 1 hour pretreatment; 12 hours) does not increase intracellular GSH levels, but GSH monoester does. D-NAC can not enhance hypoxic apoptosis. This demonstrate that GSH rather than D-NAC or NAC is responsible for enhancing hypoxic apoptosis.

医药

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