42835-89-2 6-氟-1,2,3,4-四氢-2-甲基喹啉

危险性质：非危险化学品

化学合成。

化学合成

合成路线 1（1. 合成：42835-89-2）

产率：98% 合成条件：With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 1,2,3,4,5-pentakis(methoxycarbonyl)cyclopentadiene In chloroform at 20℃; for 2 h; 实验步骤：一般步骤：在烘箱干燥的烧瓶上安装磁力搅拌棒，并加入2-取代的喹啉（0.1mmol），PCCP（1mol％），Hantzsch二氢吡啶（3.0当量）和CHCl 3（2mL）。 将得到的混合物在室温下搅拌2小时。 减压除去溶剂，残余物通过硅胶柱色谱纯化，用己烷/ EtOAc（20：1）作为洗脱剂，得到相应的1,2,3,4-四氢喹啉 参考文献：

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