1124382-72-4 2-氨基-8-溴[1,2,4]三唑并[1,5-a]吡啶

危险性质：非危险化学品

化学合成。

医药

合成路线 1（1. 合成：1124382-72-4）

产率：96% 合成条件：With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine In methanol; ethanol at 20℃; for 6 h; 实验步骤：对溶胶。 向中间体50（55g，181mmol）的EtOH（300mL）溶液中加入MeOH（300mL），盐酸羟胺（62.83g，904mmol）和DIPEA（694mL，543mmol）。 上午 在r.t.搅拌 6小时 将混合物真空浓缩，将残余物悬浮在DIPE中。 滤出沉淀物。 产量：37g中间体51（产率96％）。 参考文献：

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