化学合成。
化学合成
合成路线 1（1. 合成：3638-04-8）
产率：86.2%
合成条件：With sodium hydrogencarbonate In water at 20 - 30℃;
实验步骤：（3）中间体（c）的生产：; 将136mL水加入到1.1L甲醇中，然后向其中加入182g（2.17mol）碳酸氢钠并在室温下搅拌。 在该温度下，向其中分批加入200g（1.08mol）氰尿酰氯。 添加后，将内部温度升高至30℃。 在该温度下搅拌30分钟，然后加入500mL水，过滤出沉淀的固体，用500mL水洗涤，倒入300mL甲醇，干燥，得到168g 上述中间体（c）（白色粉末，产率86.2％）。 所得中间体（c）的NMR数据如下：1H-NMR（300MHz，CDCl3）：4.14（s，3H）
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