- Fraction Csp3
- 0.5
- GI absorption
- High
- Log K p (skin permeation)
- -6.58 cm/s
- Log P o/w (MLOGP)
- 0.55
- Log P o/w (SILICOS-IT)
- -0.77
- Log P o/w (WLOGP)
- -0.45
- Log P o/w (XLOGP3)
- 1.93
- Log P o/w (iLOGP)
- 0.0
- Log S (Ali)
- -2.54
- Log S (ESOL)
- -2.78
- Log S (SILICOS-IT)
- -1.87
- Molar Refractivity
- 84.3
- Num. H-bond acceptors
- 3.0
- Num. H-bond donors
- 2.0
- Num. arom. heavy atoms
- 6
- Num. heavy atoms
- 18
- Num. rotatable bonds
- 3
- P-gp substrate
- Yes
- Solubility
- 0.447 mg/ml ; 0.00165 mol/l
- Synthetic accessibility
- 2.24
- TPSA
- 46.94 Ų
- 储存条件
- Inert atmosphere,2-8°C
- 精确质量
- 270.130646
