作为含氟哌啶类医药中间体，用于相关药物分子的合成。
医药
合成路线 1（1. 合成：211108-50-8）
产率：99%
合成条件：With Selectfluor In acetonitrile at 20 - 40℃; for 2.16 h;
实验步骤：步骤B：3-氟-4-氧代哌啶-1-羧酸叔丁酯的制备： 在环境温度下，向4-（三甲基甲硅烷基氧基）-5,6-二氢吡啶-1（2H） - 羧酸叔丁酯（64.4g，237mmol）的无水ACN（1.5L）溶液中加入Selectfluor（92.5g，261）。 在10分钟内分批分离，在此期间观察到轻微的放热（至40℃）。 将混合物搅拌2小时，然后浓缩至干，并在EtOAc和盐水之间分配。 水层用EtOAc萃取，合并的有机相用盐水洗涤，用Na 2 SO 4干燥，过滤并浓缩，得到51g（99％）所需产物，为固体。
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