596-85-0 (4AR)-反式-5-(1,5,5,8AS-四甲基-2-亚甲基十氢-1-萘基)-(3R)-甲基-1-戊烯-3-醇

WGK Germany:3

• 生物活性 Manool 是丹参中的二萜。Manool 在癌细胞中诱导选择性的细胞毒性。Manool 使癌细胞停滞在细胞周期的 G(2)/M 期。
• 体外研究 Manool exhibits higher cytotoxic activity against HeLa (IC 50 =6.7 µg/mL) and U343 (IC 50 =6.7 µg/mL) cells. Manool exhibits a protective effect against chromosome damage induced by MMS in HepG2 cells.

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