化学合成。
化学合成
合成路线 1（1. 合成：30450-62-5）
产率：85%
合成条件：Stage #1: at -10 - 10℃; for 3.50 h; Stage #2: With sodium carbonate In water at 0℃;
实验步骤：用冰/盐浴将浓硫酸（30.00mL）冷却至-10℃。 在1小时内同时加入1,2,3,4-四氢 - 喹啉（10.60g，75.60mmol）和硝酸（99.5％，4.80g，75.60mmol）的硫酸（15.00mL）溶液。 使反应混合物的温度不超过10℃。然后将混合物在-5℃下搅拌2.5小时，然后倒在冰上并用碳酸钠（0.10kg）处理直至pH 8-9为止。 到达。 过滤固体，用水洗涤，然后溶解在二氯甲烷中。 用水洗涤有机相，用硫酸镁干燥并蒸发。 得到7-硝基-1,2,3,4-四氢 - 喹啉，为粘性棕色油状物，13.70g（85％），纯度84％。
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