化学合成。
化学合成
合成路线 1（1. 合成：17570-98-8）
产率：97.8%
合成条件：at 15 - 75℃; for 2 h;
实验步骤：在15℃，将溴（1.52mL，9.72mmol）缓慢滴加到30％HBr / HOAc（12mL）中的2-乙酰基 - 吡啶（3g，2.78mmol）中，并在滴加完成后，将反应溶液在40℃下滴加。 搅拌1小时，然后在75℃搅拌1小时。 将反应溶液冷却至20℃，向其中加入Et 2 O（30mL），在该温度下搅拌30分钟，过滤得到的黄色沉淀，用10mL乙醚洗涤沉淀物，并干燥至（6.81g，97.8）。 百分）。
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