- Aromatic heavy atoms
- 5
- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- Brenk alert
- 0.0
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Egan compliance
- 0.0
- Fraction Csp3
- 0.4
- GI absorption
- High
- H-bond acceptors
- 1.0
- H-bond donors
- 1.0
- Heavy atoms
- 9
- Leadlikeness
- 1.0
- Lipinski compliance
- 0.0
- LogP
- 1.79880
- LogP (MLOGP)
- 0.59
- LogP (SILICOS-IT)
- 2.05
- LogP (WLOGP)
- 2.19
- LogP (XLOGP3)
- 1.91
- LogP (iLOGP)
- 0.0
- Molar Refractivity
- 43.19
- Muegge compliance
- 1.0
- P-gp substrate
- No
- PSA
- 56.39 Ų
- Rotatable bonds
- 2
- Skin permeation coefficient (Log K p)
- -5.95 cm/s
- Synthetic accessibility
- 2.31
- Veber compliance
- 0.0
- 储存条件
- 室温，保存在惰性气体中
- 拓扑极性表面积
- 56.39 Ų
- 水溶解性
- 0.747 mg/ml ; 0.00454 mol/l
- 精确质量
- 164.01700
